Résumé
The question of whether a functional variant in the promoter of the serotonin transporter gene (5-HTTLPR) influences response to adversity and/or antidepressants has generated great interest and controversy. A review of the literature suggests that the issue is complicated by differences in methodology and sample ethnicity. When these confounders are accounted for, there probably is a real, if small, effect of 5-HTTLPR on response to both serotonin reuptake inhibitors and environmental adversity.
Langue d'origine | English |
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Pages (de-à) | 424-427 |
Nombre de pages | 4 |
Journal | British Journal of Psychiatry |
Volume | 198 |
Numéro de publication | 6 |
DOI | |
Statut de publication | Published - juin 2011 |
Publié à l'externe | Oui |
ASJC Scopus Subject Areas
- Psychiatry and Mental health
PubMed: MeSH publication types
- Editorial
- Comment