CD46, a primate-specific receptor for measles virus

Ruth E. Dörig; Anne Marcil; Christopher D. Richardson

doi:10.1016/0966-842X(94)90447-2

CD46, a primate-specific receptor for measles virus

Ruth E. Dörig, Anne Marcil, Christopher D. Richardson

Research output: Contribution to journal › Review article › peer-review

42 Citations (Scopus)

Abstract

Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.

Original language	English
Pages (from-to)	312-318
Number of pages	7
Journal	Trends in Microbiology
Volume	2
Issue number	9
DOIs	https://doi.org/10.1016/0966-842X(94)90447-2
Publication status	Published - Sept 1994
Externally published	Yes

ASJC Scopus Subject Areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0966-842X(94)90447-2

Cite this

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title = "CD46, a primate-specific receptor for measles virus",

abstract = "Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.",

author = "D{\"o}rig, {Ruth E.} and Anne Marcil and Richardson, {Christopher D.}",

year = "1994",

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AU - Marcil, Anne

AU - Richardson, Christopher D.

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AB - Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.

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DO - 10.1016/0966-842X(94)90447-2

M3 - Review article

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JO - Trends in Microbiology

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ER -

CD46, a primate-specific receptor for measles virus

Abstract

ASJC Scopus Subject Areas

UN SDGs

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