CD46, a primate-specific receptor for measles virus

Ruth E. Dörig, Anne Marcil, Christopher D. Richardson

Résultat de recherche: Review articleexamen par les pairs

42 Citations (Scopus)

Résumé

Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.

Langue d'origineEnglish
Pages (de-à)312-318
Nombre de pages7
JournalTrends in Microbiology
Volume2
Numéro de publication9
DOI
Statut de publicationPublished - sept. 1994
Publié à l'externeOui

ASJC Scopus Subject Areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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