CD46, a primate-specific receptor for measles virus

Ruth E. Dörig; Anne Marcil; Christopher D. Richardson

doi:10.1016/0966-842X(94)90447-2

CD46, a primate-specific receptor for measles virus

Ruth E. Dörig, Anne Marcil, Christopher D. Richardson

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42 Citas (Scopus)

Resumen

Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.

Idioma original	English
Páginas (desde-hasta)	312-318
Número de páginas	7
Publicación	Trends in Microbiology
Volumen	2
N.º	9
DOI	https://doi.org/10.1016/0966-842X(94)90447-2
Estado	Published - sep. 1994
Publicado de forma externa	Sí

ASJC Scopus Subject Areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

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abstract = "Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.",

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CD46, a primate-specific receptor for measles virus

Resumen

ASJC Scopus Subject Areas

ODS de las Naciones Unidas

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