Abstract
Streptococcus mutans NG5 failed to anchor antigen P1 to the cell surface, and such a failure could be attributed to a defective SrtA, which was made defective by a point mutation within the srtA gene. Without a functional SrtA, S. mutans NG5 was not able to perform a number of cell surface-related activities, including saliva-mediated adherence and aggregation.
| Original language | English |
|---|---|
| Pages (from-to) | 4314-4317 |
| Number of pages | 4 |
| Journal | Infection and Immunity |
| Volume | 72 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2004 |
ASJC Scopus Subject Areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't
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Lee, S. F., & McGavin, M. K. H. (2004). Identification of a point mutation resulting in loss of cell wall anchoring activity of SrtA of Streptococcus mutans NG5. Infection and Immunity, 72(7), 4314-4317. https://doi.org/10.1128/IAI.72.7.4314-4317.2004