Identification of a point mutation resulting in loss of cell wall anchoring activity of SrtA of Streptococcus mutans NG5

Song F. Lee, Mary K.H. McGavin

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

16 Citas (Scopus)

Resumen

Streptococcus mutans NG5 failed to anchor antigen P1 to the cell surface, and such a failure could be attributed to a defective SrtA, which was made defective by a point mutation within the srtA gene. Without a functional SrtA, S. mutans NG5 was not able to perform a number of cell surface-related activities, including saliva-mediated adherence and aggregation.

Idioma originalEnglish
Páginas (desde-hasta)4314-4317
Número de páginas4
PublicaciónInfection and Immunity
Volumen72
N.º7
DOI
EstadoPublished - jul. 2004

ASJC Scopus Subject Areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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