Microbedb: A locally maintainable database of microbial genomic sequences

Morgan G.I. Langille, Matthew R. Laird, William W.L. Hsiao, Terry A. Chiu, Jonathan A. Eisen, Fiona S.L. Brinkman

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Analysis of microbial genomes often requires the general organization and comparison of tens to thousands of genomes both from public repositories and unpublished sources. MicrobeDB provides a foundation for such projects by the automation of downloading published, completed bacterial and archaeal genomes from key sources, parsing annotations of all genomes (both public and private) into a local database, and allowing interaction with the database through an easy to use programming interface. MicrobeDB creates a simple to use, easy to maintain, centralized local resource for various large-scale comparative genomic analyses and a back-end for future microbial application design.

Original languageEnglish
Article numberbts273
Pages (from-to)1947-1948
Number of pages2
JournalBioinformatics
Volume28
Issue number14
DOIs
Publication statusPublished - Jul 2012

Bibliographical note

Funding Information:
Funding: This work was supported by the Canadian Institutes of Health Research, Michael Smith Foundation for Health Research, Genome Canada, and Gordon and Betty Moore Foundation.

ASJC Scopus Subject Areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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Langille, M. G. I., Laird, M. R., Hsiao, W. W. L., Chiu, T. A., Eisen, J. A., & Brinkman, F. S. L. (2012). Microbedb: A locally maintainable database of microbial genomic sequences. Bioinformatics, 28(14), 1947-1948. Article bts273. https://doi.org/10.1093/bioinformatics/bts273