A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila

Ann Karen C. Brassinga; Margot F. Hiltz; Gary R. Sisson; Michael G. Morash; Nathan Hill; Elizabeth Garduno; Paul H. Edelstein; Rafael A. Garduno; Paul S. Hoffman

doi:10.1128/JB.185.15.4630-4637.2003

A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila

Ann Karen C. Brassinga, Margot F. Hiltz, Gary R. Sisson, Michael G. Morash, Nathan Hill, Elizabeth Garduno, Paul H. Edelstein, Rafael A. Garduno, Paul S. Hoffman

Medicine

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

47 Citas (Scopus)

Resumen

Nucleotide sequence analysis of an ∼80-kb genomic region revealed an ∼65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ∼65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.

Idioma original	English
Páginas (desde-hasta)	4630-4637
Número de páginas	8
Publicación	Journal of Bacteriology
Volumen	185
N.º	15
DOI	https://doi.org/10.1128/JB.185.15.4630-4637.2003
Estado	Published - ago. 2003

ASJC Scopus Subject Areas

Microbiology
Molecular Biology

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title = "A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila",

abstract = "Nucleotide sequence analysis of an ∼80-kb genomic region revealed an ∼65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ∼65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.",

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AU - Brassinga, Ann Karen C.

AU - Hiltz, Margot F.

AU - Sisson, Gary R.

AU - Morash, Michael G.

AU - Hill, Nathan

AU - Garduno, Elizabeth

AU - Edelstein, Paul H.

AU - Garduno, Rafael A.

AU - Hoffman, Paul S.

PY - 2003/8

Y1 - 2003/8

N2 - Nucleotide sequence analysis of an ∼80-kb genomic region revealed an ∼65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ∼65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.

AB - Nucleotide sequence analysis of an ∼80-kb genomic region revealed an ∼65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ∼65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.

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DO - 10.1128/JB.185.15.4630-4637.2003

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JF - Journal of Bacteriology

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A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila

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