A comparison of I125 Clq binding, Raji cell binding, and lymphocytotoxic activity in multiple sclerosis

Alan L. Schocket; Ronald I. Carr; Melissa A. Hardtke

doi:10.1016/0090-1229(80)90120-8

A comparison of I¹²⁵ Clq binding, Raji cell binding, and lymphocytotoxic activity in multiple sclerosis

Alan L. Schocket, Ronald I. Carr, Melissa A. Hardtke

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13 Citas (Scopus)

Resumen

Sera from 48 patients with chronic multiple sclerosis (MS) were examined for the presence of immune complexes using both the I¹²⁵ Clq binding assay and the Raji cell assay. Lymphocytotoxic antibodies were also measured. Circulating complexes were found in only four patients by both assays. There was complete agreement between the two assays and no relationship between the presence of immune complexes and lymphocytotoxic antibodies. The results of this study fail to show a significant increase in circulating immune complexes in our patients with MS.

Idioma original	English
Páginas (desde-hasta)	477-481
Número de páginas	5
Publicación	Clinical Immunology and Immunopathology
Volumen	17
N.º	3
DOI	https://doi.org/10.1016/0090-1229(80)90120-8
Estado	Published - 1980
Publicado de forma externa	Sí

ASJC Scopus Subject Areas

Immunology and Allergy
Pathology and Forensic Medicine
Immunology

PubMed: MeSH publication types

Comparative Study
Journal Article

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10.1016/0090-1229(80)90120-8

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abstract = "Sera from 48 patients with chronic multiple sclerosis (MS) were examined for the presence of immune complexes using both the I125 Clq binding assay and the Raji cell assay. Lymphocytotoxic antibodies were also measured. Circulating complexes were found in only four patients by both assays. There was complete agreement between the two assays and no relationship between the presence of immune complexes and lymphocytotoxic antibodies. The results of this study fail to show a significant increase in circulating immune complexes in our patients with MS.",

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AU - Carr, Ronald I.

AU - Hardtke, Melissa A.

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