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• 2021

  A modeling approach to derive baseline risk estimates for GRADE recommendations: Concepts, development, and results of its application to the American Society of Hematology 2019 guidelines on prevention of venous thromboembolism in surgical hospitalized patients

  Morgano, G. P., Wiercioch, W., Anderson, D. R., Brożek, J. L., Santesso, N., Xie, F., Cuker, A., Nieuwlaat, R., Akl, E. A., Darzi, A. J., Yepes-Nuñez, J. J., Exteandia-Ikobaltzeta, I., Rahman, M., Rajasekhar, A., Rogers, F., Tikkinen, K. A. O., Yates, A. J., Dahm, P. & Schünemann, H. J., Dec 2021, In: Journal of Clinical Epidemiology. 140, p. 69-78 10 p.

  Medicine

  Research output: Contribution to journal › Article › peer-review

• A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation

  Schanin, J., Gebremeskel, S., Korver, W., Falahati, R., Butuci, M., Haw, T. J., Nair, P. M., Liu, G., Hansbro, N. G., Hansbro, P. M., Evensen, E., Brock, E. C., Xu, A., Wong, A., Leung, J., Bebbington, C., Tomasevic, N. & Youngblood, B. A., Mar 2021, In: Mucosal Immunology. 14, 2, p. 366-376 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  65 Citations (Scopus)

• A multi-OMIC characterisation of biodegradation and microbial community succession within the PET plastisphere

  Wright, R. J., Bosch, R., Langille, M. G. I., Gibson, M. I. & Christie-Oleza, J. A., Dec 2021, In: Microbiome. 9, 1, 141.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  99 Citations (Scopus)

• An age-independent hospital record-based frailty score correlates with adverse outcomes after heart surgery and increased health care costs

  Sarkar, S., MacLeod, J. B., Hassan, A., Dutton, D. J., Brunt, K. R. & Légaré, J. F., Dec 2021, In: JTCVS Open. 8, p. 491-502 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Analyzing association rules for graft failure following deceased and live donor Kidney transplantation

  Naqvi, S. A. A., Tennankore, K., Vinson, A. & Abidi, S. S. R., Jul 1 2021, Public Health and Informatics: Proceedings of MIE 2021. IOS Press, p. 188-192 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access
  1 Citation (Scopus)

• A national study of choanal atresia in tertiary care centers in Canada – part I: clinical presentation

  National Choanal Atresia Study Working Group, Dec 2021, In: Journal of Otolaryngology - Head and Neck Surgery. 50, 1, 45.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management

  National Choanal Atresia Study Working Group, Dec 2021, In: Journal of Otolaryngology - Head and Neck Surgery. 50, 1, 46.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• A Nationwide Cohort Study of Nonrandom Mating in Schizophrenia and Bipolar Disorder

  Greve, A. N., Uher, R., Als, T. D., Jepsen, J. R. M., Mortensen, E. L., Gantriis, D. L., Ohland, J., Burton, B. K., Ellersgaard, D., Christiani, C. J., Spang, K. S., Hemager, N., Plessen, K. J., Thorup, A. A. E., Bliksted, V., Nordentoft, M. & Mors, O., Sept 1 2021, In: Schizophrenia Bulletin. 47, 5, p. 1342-1350 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Anatomical and neurochemical organization of the serotonergic system in the mammalian brain and in particular the involvement of the dorsal raphe nucleus in relation to neurological diseases

  Steinbusch, H. W. M., Dolatkhah, M. A. & Hopkins, D. A., Jan 2021, 5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance - Part B. Di Giovanni, G., Di Giovanni, G. & De Deurwaerdere, P. (eds.). Elsevier B.V., p. 41-81 41 p. (Progress in Brain Research; vol. 261).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  29 Citations (Scopus)

• Anatomical distribution and expression of CYP in humans: Neuropharmacological implications

  Fanni, D., Pinna, F., Gerosa, C., Paribello, P., Carpiniello, B., Faa, G. & Manchia, M., Aug 2021, In: Drug Development Research. 82, 5, p. 628-667 40 p.

  Research output: Contribution to journal › Review article › peer-review
  24 Citations (Scopus)

• An Environmental Scan and Evaluation of Quality Indicators Across Canadian Kidney Transplant Centers

  Glavinovic, T., Vinson, A. J., Silver, S. A. & Yohanna, S., 2021, In: Canadian Journal of Kidney Health and Disease. 8

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• An environmental scan of virtual "walk-in" clinics in canada: Comparative study

  Matthewman, S., Spencer, S., Lavergne, M. R., McCracken, R. K. & Hedden, L., Jun 2021, In: Journal of Medical Internet Research. 23, 6, e27259.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Citations (Scopus)

• An Ethics-Informed, Comparative Analysis of Uterus Transplantation and Gestational Surrogacy for Uterine Factor Infertility in High-Income Countries

  Kirby, J., Sept 2021, In: Journal of Bioethical Inquiry. 18, 3, p. 417-427 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• An Evaluation of Device-Measured Physical Activity Levels of Patients With Nonpermanent Atrial Fibrillation

  Reed, J. L., Blanchard, C. M. & Parkash, R., Nov 1 2021, In: Journal of Cardiopulmonary Rehabilitation and Prevention. 41, 6, p. 440-442 3 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)

• A New 3-D Imaging Technique Integrating Ultrafast Compounding, Hadamard Encoding, and Reconfigurable Fresnel Lensing

  Latham, K., Samson, C. & Brown, J., May 2021, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 68, 5, p. 1618-1627 10 p., 9285280.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• A New Approach to Evaluate and Reduce Uncertainty of Model-Based Biodiversity Projections for Conservation Policy Formulation

  Myers, B. J. E., Weiskopf, S. R., Shiklomanov, A. N., Ferrier, S., Weng, E., Casey, K. A., Harfoot, M., Jackson, S. T., Leidner, A. K., Lenton, T. M., Luikart, G., Matsuda, H., Pettorelli, N., Rosa, I. M. D., Ruane, A. C., Senay, G. B., Serbin, S. P., Tittensor, D. P. & Douglas Beard, T., Dec 1 2021, In: BioScience. 71, 12, p. 1261-1273 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• A new approach to improve the hemodynamic assessment of cardiac function independent of respiratory influence

  Ogilvie, L. M., Edgett, B. A., Gray, S., Al-Mufty, S., Huber, J. S., Brunt, K. R. & Simpson, J. A., Dec 2021, In: Scientific Reports. 11, 1, 17223.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• An Examination of the Role of Socioeconomic Status in the Relationship between Depression and Prostate Cancer Survivorship in a Population-Based Sample of Men from Atlantic Canada

  Ilie, G., Rutledge, R. & Sweeney, E., Mar 2021, In: Oncology. 99, 4, p. 260-270 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• An examination of three prescribing cascades in a cohort of older adults with dementia

  Trenaman, S. C., Bowles, S. K., Kirkland, S. & Andrew, M. K., Dec 2021, In: BMC Geriatrics. 21, 1, 297.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• An exploration of mercaptopurine/methotrexate tolerance during maintenance therapy in children with acute lymphoblastic leukemia

  Whiley, A. C., Price, V. & MacDonald, T., Oct 2021, In: Journal of Oncology Pharmacy Practice. 27, 7, p. 1631-1636 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• An extensive clean-up method for extraction of 17β-estradiol from eel aquaculture waste solids for quantitation via high-performance liquid chromatography tandem-mass spectrometry

  Sweeney, C. L., Brown, C. A. M., Bennett, J. L., Ross, N. W. & Gagnon, G. A., Sept 15 2021, In: Aquaculture. 542, 736873.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• An instrumented cochlea model for the evaluation of cochlear implant electrical stimulus spread

  Jiang, C., Singhal, S., Landry, T., Roberts, I., De Rijk, S., Brochier, T., Goehring, T., Tam, Y., Carlyon, R., Malliaras, G. & Bance, M., Jul 2021, In: IEEE Transactions on Biomedical Engineering. 68, 7, p. 2281-2288 8 p., 9354566.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Citations (Scopus)

• An international Delphi consensus study to define motivational communication in the context of developing a training program for physicians

  Dragomir, A. I., Boucher, V. G., Bacon, S. L., Gemme, C., Szczepanik, G., Corace, K., Campbell, T. S., Vallis, M. T., Garber, G., Rouleau, C., Rabi, D., Diodati, J. G., Ghali, W. & Lavoie, K. L., Feb 1 2021, In: Translational Behavioral Medicine. 11, 2, p. 642-652 11 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• An in vivo genome-wide shRNA screen identifies BCL6 as a targetable biomarker of paclitaxel resistance in breast cancer

  Sultan, M., Nearing, J. T., Brown, J. M., Huynh, T. T., Cruickshank, B. M., Lamoureaux, E., Vidovic, D., Dahn, M. L., Fernando, W., Coyle, K. M., Giacomantonio, C. A., Langille, M. G. I. & Marcato, P., Aug 2021, In: Molecular Oncology. 15, 8, p. 2046-2064 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• A novel framework to protect animal data in a world of ecosurveillance

  Lennox, R. J., Harcourt, R., Bennett, J. R., Davies, A., Ford, A. T., Frey, R. M., Hayward, M. W., Hussey, N. E., Iverson, S. J., Kays, R., Kessel, S. T., McMahon, C., Muelbert, M., Murray, T. S., Nguyen, V. M., Pye, J. D., Roche, D. G., Whoriskey, F. G., Young, N. & Cooke, S. J., 2021, In: BioScience. 70, 6, p. 468-476 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  26 Citations (Scopus)

• A novel protein from ectocarpus sp. Improves salinity and high temperature stress tolerance in arabidopsis thaliana

  Rathor, P., Borza, T., Stone, S., Tonon, T., Yurgel, S., Potin, P. & Prithiviraj, B., Feb 2 2021, In: International Journal of Molecular Sciences. 22, 4, p. 1-20 20 p., 1971.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Anterior and posterior glenoid bone augmentation options for shoulder instability: State of the art

  Calvo, E., Itoi, E., Landreau, P., Arce, G., Yamamoto, N., Ma, J., Sparavalo, S. & Wong, I., Sept 1 2021, In: Journal of ISAKOS. 6, 5, p. 308-317 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  25 Citations (Scopus)

• Antibacterial activities of physiologically stable, self-assembled peptide nanoparticles

  Nazeer, N., Simmons, J. R., Rainey, J. K., Rodriguez-Lecompte, J. C. & Ahmed, M., Nov 21 2021, In: Journal of Materials Chemistry B. 9, 43, p. 9041-9054 14 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Antibody and cell-mediated immune responses are correlates of protection against influenza infection in vaccinated older adults

  Verschoor, C. P., Andrew, M. K., Loeb, M., Pawelec, G., Haynes, L., Kuchel, G. A. & McElhaney, J. E., Jan 2021, In: Vaccines. 9, 1, p. 1-12 12 p., 25.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Anti-Cortactin Autoantibodies Are Associated With Key Clinical Features in Adult Myositis but Are Rarely Present in Juvenile Myositis

  on behalf of the Childhood Myositis Heterogeneity Collaborative Study Group, 2021, (Accepted/In press) In: Arthritis and Rheumatology.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Anti-inflammatory iron chelator, DIBI, reduces leukocyte-endothelial adhesion and clinical symptoms of LPS-induced interstitial cystitis in mice

  Hagn, G., Holbein, B., Zhou, J. & Lehmann, C., 2021, In: Clinical Hemorheology and Microcirculation. 79, 3, p. 395-406 12 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial

  Anti-IL-21–liraglutide Study Group investigators and contributors, Apr 2021, In: The Lancet Diabetes and Endocrinology. 9, 4, p. 212-224 13 p.

  Research output: Contribution to journal › Article › peer-review
  126 Citations (Scopus)

• Antimicrobial utilization and stewardship in patients with uncomplicated urinary tract infections managed by pharmacists in the community: A sub-study of the r_xoutmap trial

  Beahm, N. P., Smyth, D. J. & Tsuyuki, R. T., Sept 2021, In: JAMMI. 6, 3, p. 205-212 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Antipsychotic potential of the type 1 cannabinoid receptor positive allosteric modulator GAT211: preclinical in vitro and in vivo studies

  McElroy, D. L., Roebuck, A. J., Scott, G. A., Greba, Q., Garai, S., Denovan-Wright, E. M., Thakur, G. A., Laprairie, R. B. & Howland, J. G., Apr 2021, In: Psychopharmacology. 238, 4, p. 1087-1098 12 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Antithrombotic Therapy After Percutaneous Coronary Intervention in Patients With Atrial Fibrillation: Findings From the CONNECT AF+PCI Study

  CONNECT AF+PCI Study Investigators, Dec 2021, In: CJC Open. 3, 12, p. 1419-1427 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• An Unusual Todd's Phenomenon: Post-Ictal Prosopagnosia

  George, R. S., Sadler, R. M. & Clarke, D. B., Sept 2021, In: Canadian Journal of Neurological Sciences. 48, 5, p. 730-731 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Anxiety, depression and posttraumatic stress disorder after terrorist attacks: A general review of the literature

  Rigutto, C., Sapara, A. O. & Agyapong, V. I. O., Oct 2021, In: Behavioral Sciences. 11, 10, 140.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  35 Citations (Scopus)

• A Pan-Canadian Validation Study for the Detection of EGFR T790M Mutation Using Circulating Tumor DNA From Peripheral Blood

  Selvarajah, S., Plante, S., Speevak, M., Vaags, A., Hamelinck, D., Butcher, M., McCready, E., Grafodatskaya, D., Blais, N., Tran-Thanh, D., Weng, X., Nassabein, R., Greer, W., Walton, R. N., Lo, B., Demetrick, D., Santos, S., Sadikovic, B., Zhang, X., Zhang, T., & 4 othersSpence, T., Stockley, T., Feilotter, H. & Joubert, P., Aug 2021, In: JTO Clinical and Research Reports. 2, 8, 100212.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A Patient-Centric Tool to Facilitate Goal Attainment Scaling in Neurogenic Bladder and Bowel Dysfunction: Path to Individualization

  Goldstine, J., Knox, K., Beekman, J., Cobussen-Boekhorst, H., Conti, A., Gray, M., Inglese, G., England, A., Rodriguez, G., Stanley, J., Vaughn, S., Howlett, S. E. & Rockwood, K., Mar 2021, In: Value in Health. 24, 3, p. 413-420 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• A porcine model of endothelial glycocalyx damage by enzymatic digestion: A pilot study

  Astapenko, D., Ticha, A., Hyspler, R., Tomasova, A., Navratil, P., Maly, O., Parizkova, R. C., Cizkova, D., Huey, S. C., Lehmann, C., Malbrain, M. L. N. G. & Cerny, V., 2021, In: Clinical Hemorheology and Microcirculation. 78, 3, p. 325-338 14 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Applicability of the four-factor personality vulnerability model for substance misuse in understanding gambling behaviour and gambling problems

  Otis, E., Yakovenko, I., Sherry, S., Smith, M., Goldstein, A., Ellery, M., Loverock, A., Wild, T. C., Weilgart-Whitehead, B. & Stewart, S. H., Feb 1 2021, In: Personality and Individual Differences. 169, 110400.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Application mobile périopératoire destinée aux mères avec un accouchement par césarienne : une étude de cohorte prospective sur l’intérêt des patientes

  Translated title of the contribution: Perioperative mobile application for mothers undergoing Cesarean delivery: a prospective cohort study on patient engagementKe, J. X. C., George, R. B., Wozney, L. & Munro, A., Apr 2021, In: Canadian Journal of Anaesthesia. 68, 4, p. 505-513 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Application of machine learning to identify predators of stocked fish in Lake Ontario: using acoustic telemetry predation tags to inform management

  Klinard, N. V., Matley, J. K., Ivanova, S. V., Larocque, S. M., Fisk, A. T. & Johnson, T. B., Jan 2021, In: Journal of Fish Biology. 98, 1, p. 237-250 14 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Application of the paleolimnological method to assess metal contaminant distribution (As, Cu, Pb, Zn) in pulp mill stabilization basin sediments, Nova Scotia, Canada

  Davidson, K. B., Holmes, B. E. J., Spooner, I. S., Dunnington, D. W., Walker, T. R., Lake, C. B. & Su, C. C., Oct 2021, In: Environmental Science and Pollution Research. 28, 37, p. 51342-51355 14 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Applying augmented reality to treat Fournier's gangrene in COVID-19 positive patients whilst safeguarding the multi-disciplinary surgical team: A case series

  Alyaqout, K., AlQinai, S., Almazeedi, S., Karim, J. S., Al-Youha, S. & Al-Sabah, S., Feb 2021, In: International Journal of Surgery Case Reports. 79, p. 335-338 4 p.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access
  1 Citation (Scopus)

• Approaches to optimize patient and family engagement in hospital planning and improvement: Qualitative interviews

  Anderson, N. N., Baker, G. R., Moody, L., Scane, K., Urquhart, R., Wodchis, W. P. & Gagliardi, A. R., 2021, (Accepted/In press) In: Health Expectations.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Appropriateness of Abdominal Aortic Aneurysm Screening With Ultrasound: Potential Cost Savings With Guideline Adherence and Review of Prior Imaging

  Murray, M. & Costa, A. F., Aug 2021, In: Canadian Association of Radiologists Journal. 72, 3, p. 398-403 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A prognostic model, including quantitative fetal fibronectin, to predict preterm labour: The quids meta-analysis and prospective cohort study

  Stock, S. J., Horne, M., Bruijn, M., White, H., Heggie, R., Wotherspoon, L., Boyd, K., Aucott, L., Morris, R. K., Dorling, J., Jackson, L., Chandiramani, M., David, A., Khalil, A., Shennan, A., Van Baaren, G. J., Hodgetts-Morton, V., Lavender, T., Schuit, E., Harper-Clarke, S., & 4 othersMol, B., Riley, R. D., Norman, J. & Norrie, J., 2021, In: Health Technology Assessment. 25, 52

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• A Program of Research to Evaluate the Impact of Deceased Organ Donation Legislative Reform in Nova Scotia: The LEADDR Program

  Weiss, M. J., Krmpotic, K., Cyr, T., Dhanani, S., Dieudé, M., Dirk, J. S., Hartell, D., Isenor, C., James, L., Lucas, A., Patriquin, C., Simpson, C., Sullivan, V. L., Tennankore, K. K., Thurlow, J., Urquhart, R., Vorster, H. & Beed, S. D., 2021, (Accepted/In press) In: Transplantation Direct. e641.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• A Prospective Economic Analysis of Early Outcome Data From the Alliance A041202/ CCTG CLC.2 Randomized Phase III Trial Of Bendamustine-Rituximab Compared With Ibrutinib-Based Regimens in Untreated Older Patients With Chronic Lymphocytic Leukemia

  Cheung, M. C., Mittmann, N., Owen, C., Abdel-Samad, N., Fraser, G. A. M., Lam, S., Crump, M., Sperlich, C., van der Jagt, R., Prica, A., Couban, S., Woyach, J. A., Ruppert, A. S., Booth, A. M., Mandrekar, S. J., McDonald, G., Shepherd, L. E., Yen, H., Chen, B. E. & Hay, A. E., Nov 2021, In: Clinical Lymphoma, Myeloma and Leukemia. 21, 11, p. 766-774 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)